Description
Berberine HCL 97% powder is a highly purified, crystalline yellow powder derived from natural sources such as Coptis chinensis (Huang Lian), Berberis species, and Hydrastis canadensis (Goldenseal). This bitter-tasting compound is the hydrochloride salt of berberine, a quaternary ammonium alkaloid renowned for its pharmacological properties. With a typical purity of ≥98%, it undergoes advanced extraction and purification processes (e.g., acid-base extraction, recrystallization) to ensure consistency and safety. Free from heavy metals, microbial contaminants, and synthetic additives, it adheres to strict food-grade quality standards.
Berberine HCL 97%Function
Antimicrobial Activity:
Inhibits the growth of bacteria (Gram-positive/Gram-negative), fungi, and protozoa, making it effective against gastrointestinal infections.
Anti-inflammatory Properties:
Reduces pro-inflammatory cytokines (e.g., TNF-α, IL-6) to alleviate inflammatory conditions.
Metabolic Regulation:
Improves insulin sensitivity and glucose metabolism, supporting blood sugar management.
Lowers LDL cholesterol and triglyceride levels to promote cardiovascular health.
Antioxidant Effects:
Neutralizes free radicals and protects cells from oxidative damage.
Potential Anticancer Activity:
Studies suggest it may induce apoptosis in cancer cells and inhibit tumor growth (in preclinical research).
Specification Sheet(COA)
|
Product Name |
Berberine HCL 97% |
Country of Origin |
China |
|
Botanical latin Name |
Coptis chinensis. |
Specification |
Berberine HCL 97% |
|
Plant Part |
Dried rhizome of Coptis, Bark of Phellodendron, Root bark of Berberis (100% Natural) |
Carrier |
None |
|
Item |
Specification |
Result |
Test Methods |
|
Assay |
Berberine HCL≥97% |
97.25% |
UV |
|
Identification |
Conforms to standard |
Conforms |
TLC |
|
·Chemical Physical Control |
|||
|
Particle size |
100% pass 80 mesh |
80 mesh |
USP<786> |
|
Loss on drying |
≤5.0% |
2.15% |
USP<731> |
|
Ash Content |
≤5.0% |
1.71% |
USP<281> |
|
Loose Density |
40-70g/100ml |
46g/100ml |
USP<616> |
|
Appearance |
Fine Powder |
Conforms |
Visual |
|
Color |
Yellow |
Yellow |
Visual |
|
Odor |
Typical |
Typical |
Organoleptic |
|
Taste |
Typical |
Typical |
Organoleptic |
|
Heavy Metals |
≤10ppm |
<10ppm |
CP2020 |
|
Arsenic (As) |
≤2ppm |
≤1ppm |
ICP-MS |
|
Lead (Pb) |
≤2ppm |
≤1ppm |
ICP-MS |
|
Mercury(Hg) |
≤0.5ppm |
≤0.005ppm |
ICP-MS |
|
Cadmium(Cd) |
≤1ppm |
≤0.1ppm |
ICP-MS |
|
Pesticides Residue |
Meet USP Requirements |
Conforms |
USP34 <561> |
|
·Microbiology Control |
|||
|
Total Plate Count |
≤1,000cfu/g |
300cfu/g |
AOAC 990.12 |
|
Total Yeast & Mold |
≤100cfu/g |
15cfu/g |
AOAC 997.02 |
|
Coliforms |
≤10cfu/g |
≤3cfu/g |
AOAC |
|
Escherchia Coli |
Absent |
Conforms |
AOAC-OMA 991.14 |
|
Salmonella Species |
Absent |
Conforms |
AOAC-RI 061301 |
|
Staphylococcus aurreus |
Absent |
Conforms |
AOAC-OMA 2003.07 |
|
·General Status |
|||
|
Sterilization Method |
High Temperature & Pressure |
Conforms |
/ |
|
·Packing & Storage |
Packed in paper-drums and two plastic-bags inside.N.W.:25kgs Store in a well-closed container. Away from moisture. |
||
|
·Shelf Life |
Three years if sealed and stored away from direct sun light and heat. |
||
|
Analyst : Yang,Yan |
QC Supervisor: Ren, Xiaofeng |
||
Our Certificate
Technological Process
Berberine HCL 97% Application
Pharmaceutical Formulations
- Antibacterial Drugs: Used in tablets/capsules for treating bacterial diarrhea, urinary tract infections, and Helicobacter pylori infections.
- Metabolic Syndrome Management: Formulated in supplements to support type 2 diabetes and hyperlipidemia.
- Topical Antimicrobials: Added to creams/ointments for skin infections and wound care.
Traditional Chinese Medicine (TCM)
- A core ingredient in TCM formulas for clearing heat, drying dampness, and detoxifying (e.g., "Huang Lian Jie Du Tang").
- Functional Foods & Beverages
- Fortified into probiotic drinks, dietary bars, and herbal teas for gut health and immune support.
- Used as a natural preservative in food products due to its antimicrobial properties.
Veterinary Medicine
- Applied in animal health products to treat diarrhea and infections in livestock/pets.
- Research & Development
- Investigated for potential therapeutic uses in neurodegenerative diseases (e.g., Parkinson's), polycystic ovary syndrome (PCOS), and antimicrobial resistance.
Our Advantage
Bestherb is a professional manufacturer of Berberine HCL powder. Berberine HCL powder are extracted from Dried rhizome of Coptis, Bark of Phellodendron, Root bark of Berberis raw materials, the quality of the raw materials have been tested and controlled, high-quality raw materials through the traditional extraction process, such as solvent extraction (extraction with water or ethanol), to retain a high level of natural nutrients. Berberine HCL are often used in food processing and dietary supplement production. We are able to produce with a content of 97% to meet the production needs of customers in different applications.
Production Equipment
R&d Center Display
Product packaging
Warehouse
FAQ
Q: Who are we?
A: Bestherb, Inc. was established in 2014. With its corporate plant located in China, Bestherb Inc. is a Hanzhong TRG branch company based in the Ontario ,CA. At Bestherb Inc. we provide top quality herbal extracts products at accommodating prices with expedited delivery to our customers all over the world. Bestherb Inc. is the gateway in the herbal importing world. As a result, our products require specific quality control measures and production procedures to meet the highest standards. We service wholesalers, distributors, and manufacturers of botanic services and products in North and South America; standing strong with fast and accurate services, extensive product line, and affordable prices.
Q: What is berberine hydrochloride used for?
A: People most commonly use berberine for diabetes, high levels of cholesterol or other fats in the blood, and high blood pressure.
Q: What kind of specifications can you offer for Berberine HCL?
A: We could offer Berberine HCL 97%
Q: If I purchase more than one product, can your company reconfigure the specifications for us?
A: We have a professional sales team, according to the customer's purchase needs, customized needs, purchase suggestions and programs.
Q: Your Extract Powder is natural source or Synthetic product?
A: Our Extract Powder is from natural plants, dried rhizome of coptis, bark of phellodendron, root bark of berberis.
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